Residents of 28 Barbary Lane continue to navigate human life, flawed love, and blind hope in 1980's San Francisco.
Frannie discovers DeDe and the children were not killed at Jonestown and hires Mary Ann to cover the story. Mother Mucca mysteriously comes to San Francisco to do "some reckoning." Prue Giroux falls for a mysterious stranger who lives in the park.
Brian's quest for Mary Ann's love is stalled while she covers DeDe's story. Anna and Royal Reichenbach fall for each other...much to Mother Mucca's dismay. DeDe sends the twins on a cruise to Alaska, not knowing that Luke is on the same cruise.
Mary Ann and DeDe head up to Alaska to hunt for the twins. Mother Mucca reveals that Royal is Anna's natural father. Jim Jones kidnaps the twins. Brian, with help from Mouse and Anna, prevents Bambi Kanataka from stealing Mary Ann's big story.
Mary Ann and DeDe's Alaskan trip turns out to be a wild goose chase, so they return home. Luke, too, has returned to California, and it's up to Prue to help reunite DeDe with her children. Mrs. Madrigal and her family hold Bambi hostage until Mary Ann can return, during which time, Mother Mucka figures out who Bambi actually is. After Mother Mucca makes her discovery, she returns home to Winnemucca. Jon resurfaces, looking to rekindle his relationship with Michael, though it's hinted at that he's becoming ill. D'Orthea returns shortly after DeDe was reunited with the twins. Mary Ann and Brian get married shortly after Mrs. Madrigal receives news that Mother Mucca has passed away.
