Original: DOPE 麻薬取締部特捜課
Rookie officer Saiki Yuto joins a secret narcotics unit and teams up with his tough instructor to take down a dangerous new drug spreading across Japan.
In the near future in Japan, Saiki (Kaito Takahashi) is scouted by the Special Investigation Division, which cracks down on the new drug DOPE, and heads to the crime scene. While he is in danger, Jinnai (Tomoya Nakamura), also from the Special Investigation Division, appears...
While Jinnai (Nakamura Tomoya) is in contact with Jiu (Iura Arata), news of a hostage situation comes in. Saiki (Takahashi Kaito), who is not happy with Jinnai's methods, tries to persuade him, but finds himself in a pinch due to the perpetrator's supernatural powers...
Saiki (Takahashi Kaito) is asked by Tsubaki (Oshinari Shugo) to keep an eye on Jinnai (Nakamura Tomoya), who is suspected of taking DOPE. Meanwhile, the Special Investigation Division succeeds in making contact with a DOPE dealer and is close to making an arrest, but...
After escaping Saiki's (Takahashi Kaito) tail, Jinnai (Nakamura Tomoya) is told new facts about his wife's case by Jiu (Iura Arata). Meanwhile, at Katsuragi's (Miura Masami) daughter's university, a student dies of drug overdose...
They hear that Tsubaki's (Oshinari Shugo) cause of death was suicide, but Saiki (Takahashi Kaito) and Jinnai (Nakamura Tomoya) suspect it may be connected to the 500 million yen theft. Meanwhile, the Special Investigation Division infiltrates a nightclub to crack down on DOPE.
Jinnai (Nakamura Tomoya) is informed by Ji-woo (Iura Arata) that the person involved in his wife's death has been identified. Meanwhile, Saiki (Takahashi Kaito) has a vision in his head after coming into contact with his mother's DOPE.
Saiki (Takahashi Kaito) sees a future in which Jinnai (Nakamura Tomoya) tries to kill Tokura (Koike Teppei), and pursues his whereabouts. It turns out that Tokura is the real culprit who murdered his wife, and the truth of the incident is finally told to Jinnai...
When Saiki (Kaito Takahashi) hears that Jinnai (Tomoya Nakamura) has escaped from a detention facility, he rebels, saying that he was only being manipulated by Jiu (Arata Iura). Meanwhile, Watanuki's (Yuko Araki) grandmother goes missing...
Saiki (Kaito Takahashi) is informed by Jiu (Arata Iura) that the game is about to begin, and an explosion occurs in Shibuya. Meanwhile, Natsume (Keita Kumai) tries to pinpoint the location of the crime, but an alarm sounds in the Special Investigation Division...
As he joins up with Jinnai (Nakamura Tomoya) and heads to Ji-woo's (Iura Arata) location, Saiki (Takahashi Kaito) predicts that he will be shot by Ji-woo in the future. What will be the outcome of the final battle with Ji-woo, and what will be the fate of Buddy and the Special Investigation Division?
