Four Southern Florida seniors share a house, their dreams, and a whole lot of cheesecake. Bright, promiscuous, clueless and hilarious, these lovely, mismatched ladies form the perfect circle of friends.
In the Pilot, Sophia arrives after her retirement home burns down and Blanche prepares to get married.
Dorothy's daughter, Kate, comes to Miami with an announcement. She's engaged to a podiatrist named Dennis. Dorothy is thrilled but her happiness quickly turns to anger when she realizes that ex-husband, Stan, is going to be invited. After 38 years of marriage, Stan had left Dorothy for a woman half her age. Dorothy threatens to make a scene at the reception which places Rose and Blanche in the role of peacemaker.
Having not dated since her husband died, Rose reluctantly agrees to go on a blind date. This date turns into a serious relationship when she is invited on a cruise which would involve sharing a stateroom.
Blanche's sister, Virginia, comes to Miami for a visit and Blanche is convinced she's after something. Later, while out to dinner, she learns just what Virginia is after, Blanche's kidney. Meanwhile, Rose and Dorothy babysit for an infant.
A doctor Dorothy dates makes a pass at Blanche. But when Blanche tells Dorothy about it, Dorothy doesn't believe her. Dorothy accuses her of being a slut and when Blanche can't take no more she orders Dorothy to move out.
Blanche's 14-year old grandson comes to Miami for a visit and brings a new meaning to the term "generation gap." Meanwhile, Dorothy studies for her French final.
In a bowling competition, it's Dorothy and Blanche verses Rose and Sophia. If Sophia and Rose win, Dorothy will allow Sophia to go back to Sicily for a visit with an old beau and if Dorothy and Blanche win Sophia will give her a pair of antique earrings.
After a Madonna concert, the girls arrive home to discover their house has been broken into. This leads the girls to seek out means to protect themselves, including a security system, guard dog and mace. Meanwhile, Rose becomes so paranoid that the robbers will come back she goes so far as to purchase a gun.
Blanche goes all out to try to look good for her latest beau, her aerobics instructor half her age. Meanwhile, Rose's dynamic mother comes for a visit and gets fed up with Rose's ""mothering"" ways.
After a dinner party, Sophia suffers an apparent heart attack with a heavy storm delaying the paramedics.
Dorothy's ex-husband, Stan shows up to settle a piece of land they bought on their honeymoon. This leads to Dorothy and Stan spending the night together. Meanwhile, Rose and Blanche plan a vacation that Sophia is not invited on.
Dorothy's sister, Gloria, comes to Miami for a visit and asks Sophia to come live with her in California. Meanwhile, Blanche is furious when Rose is cast as Lady Macbeth, in a local play, and not her.
Rose has been dating Dr. Jonathan Newman and begins to think their relationship is leading to the altar. However she begins to have second thoughts especially since he's a midget.
Dorothy latest boyfriend Glen gives her a shock when he tells her that he's married. She surprises herself when she finds herself sneaking around to be with him. Meanwhile, Blanche unloads her old car on Rose in order to buy a new one.
Late one evening, Rose brings a man home and they spend the night together. However, in the morning she finds that he has passed away. Even worse, she later discovers he was married.
Rose is apprehensive about a visit from her daughter and granddaughter, since their reason for coming is to settle Rose's late-husband's will. Meanwhile, Blanche gets caught up in the tabloids of a society murder.
Blanche's visiting niece is a chip right off the old block when she dates a different man all night every night. Meanwhile, Dorothy does battle with a mouse living in the house.
Dorothy is hesitant about having foot surgery just as she was scheduled to tap dance with Blanche and Rose at a dance recital.
Blanche is romanced by a wealthy suitor who she learns has several small children. This fact dampens his proposal of marriage. Meanwhile, Dorothy and Rose go to bat with the bathroom plumbing.
Blanche's psychology professor sexually harasses her when she goes to him for help on a difficult test. Blanche's professor makes her an harassing deal: If she has sex with him, he'll give her an "A" for the exam. Meanwhile, Dorothy, Rose and Sophia each try to get a hold of tickets for a sold out Frank Sinatra concert.
A week before an awards ceremony, Blanche, Dorothy and Rose each come down with a nasty flu, which compounds their arguing over who will win a prestigious award.
When Rose loses her job at the grief center, she begins searching for other sources of work. Meanwhile, Blanche tries to lose a few pounds and Dorothy is excited when a man she once had a crush on, contacts her and asks her out.
Rose's sister, Lily must deal with life as a blind person after recently losing her sight. Meanwhile, the girls hold a garage sale in order to buy a new TV but find it hard to part with things.
Blanche's father, Big Daddy, comes to Miami for a visit, with an announcement, he's sold the family plantation and is setting out to become a country singer. Meanwhile, Sophia places a curse on a neighbor who refuses to remove his tree that fell over onto the lanai during a storm.
One night after watching Psycho, the girls find it hard to sleep so they stay up and reminisce about how they all came to live with one another.
